TB- 500 is a synthetic version of a naturally occurring peptide present in animal cells thymosin beta 4. The potent peptide falls under the category of sixteen related molecules, which have a high sequence conservation and localization in most circulating cells and tissues. TB-500 binds to actin and prevents the polymerization of actin and in eukaryotic cells, it is the actin-sequestering molecule. The peptide has been largely linked to recovery, as it is essential in the formation in new blood vessels, muscle fibers, blood cell production, and muscle cell production. TB-500 was identified as the gene that was responsible for up regulation of up to 4-6 times during the formation of new blood cells from the existing cells. The peptide is found in wound fluid and according to studies, if the hormone is administered subcutaneously, it promotes wound healing, speeds up muscle recovery and initiates muscle building.
In other aspects, the main function of TB-500 is to promote the migration of cells from one region to another, this occurs via the interaction of the peptide and actin in the cell cytoskeleton. The central small amino acid long actin binding domain has wound healing and blood cell formation properties. These characteristics are accentuated by the migration of the endothelial cells and keratinocytes. Moreover, it is vital in production of extracellular matrix degrading enzymes. Research indicates that TB-500 is a natural wound repair factor, which has anti-inflammatory properties, One of the main key features of TB-500 is the ability to regulate protein building cell actin, which is an important component in cell structure and its motility. Actin is present in all proteins in cells and plays a crucial role in genetic makeup,the main function of the TB 500 peptide