Thymosin beta 500 (TB 500)

Thymosin is a hormone that is produced in the thymus glands, the main role of the hormone is to induce the production of T cells, Moreover, the development of B-cells into plasma cells is mediated by thymosin and the B-cells produce antibodies, the most common form of thymosin is beta 4. Beta 4 forms an integral part in the actin sequestering proteins; it is the primary regulator of non-polymerized actin. The maintenance of the required level of cytoplasmic free G-actin monomers is one of the functions of beta thymosin. The non-polymerized actin promotes the elongation of filaments and it stimulates the influx of monomers between the thymosin bound pool and the F-actin. TB-500 on the other hand is a synthetic version of the natural beta 4, which is produced by the thymus gland. TB 500 also commonly known as thymosin beta 500 is made up of molecular formula C212H350N56O78S and the polypeptide has a molecular mass of 4.963-kilo Daltons.

Thymosin beta 4 is important in the differentiation, proliferation, and maturity of endothelial cells, moreover the functioning of the cells is largely dependent on the level of the hormone. Cell proliferation and maturity is essential for the growth of new cells, which promotes the rejuvenation of dermal tissues when the dead cells exfoliate. Studies reveal that thymosin beta 4 has a main function in collagen deposition this is possible through the decrease in inflammation and the migration of keratin cells on the peripheral organs. The creation of actin-sequestering molecule is important in preventing the polymerization of actin. Research reveals that TB-500 up regulates the formation of blood vessels by five times , the formation of new blood vessels is highly important because it aids in the delivery of oxygen to different parts of the body.

When the amino acid binds to actin it causes the production an extracellular matrix-degrading enzyme coupled with the migration of cells to the cytoskeleton region. Matrix degrading enzymes and TB-500 induce the migration of keratin and endothelial cells. There are 43 amino acids in the structure of TB-500 these are specifically designed to interact with different molecules and cells to enhance cell regeneration and tissue repair. One of the main differences of thymosin beta 4 is that it can pass through cells and tissues easily and cause interaction, which is important in cell development. TB-500 promotes the transfer of genetic information, which causes tissue repair, and proliferation of cells. Other studies show that the hormone can induce muscle recovery, repair of damaged tissues and cell development. TB-500 has a higher effectiveness and potency than the natural thymosin beta 4, and with the anti-inflammatory characteristics, the hormone promotes cell generation, maturity and development. TB-500 alleviates alopecia and reduces inflammation as well increase in cell-to-cell exchange. If interested in conducting medical research, you can buy peptides at American Science Labs.